This nomogram is used to predict the probability of a patient having a minimal prostate cancer, as well as the risk of actually
having an unexpected aggressive (high-risk 6) tumour.
|Age in years|
|Prostate TRUS volume in cubic centimetres|
|Total number of cores positive for cancer|
|Total number of cores taken|
|Longest cancer length in mm|
|Total cancer length less than 6mm?|
|Percentage of Gleason pattern 4/5 present1, 2||%|
IMPORTANT: These results are aimed at providing a guide to assist the specialist urologist and patient in making a more informed decision regarding further treatment. This statistical report should be viewed in conjunction with the clinical features and should not be considered in isolation. This report does not take into account results from previous prostate biopsies.
3 The Uropath Nomogram is based on biopsy and radical prostatectomy results for 2,525 Australian men. The Nomogram calculation is based on patient age, TRUS volume (cc), PSA density, % positive biopsy cores, longest cancer length (mm), total cancer length (mm), % Gleason grade 4/5
4 Men with a Uropath Nomogram probability of:
a) 20% or higher have the same chance of high-risk disease as men meeting the PRIAS criteria for active surveillance, but have a greater likelihood of minimal cancer as compared to the PRIAS criteria
b) 30% or higher have the same chance of high-risk disease as men meeting the Epstein Criteria for predicting minimal cancer, but have a greater likelihood of minimal cancer as compared to the Epstein criteria
5 Minimal cancer is defined as total tumour volume < 0.5cc, Gleason sum = 6 and confined to the prostate
6 High-risk cancer is defined as a tumour having one or more of the following: positive surgical margins, extracapsular extension, seminal vesicle invasion, = 50% Gleason patterns 4 or 5, or tumour volume = 4.0cc